Inimical Interaction of Tobacco with Drugs

Consumption of tobacco in any form is bad as it has inimical interaction with a majority of drugs/medicines in addition to its other bad effects and health hazards. There are thousands of chemical substances in the tobacco and the smoke of its products like cigarette and bidi. Nicotine, tar and carbon monoxide are three most damaging chemical substances present in the smoke of cigarette and bidi. Smoking and chewing of tobacco would affect your metabolism and physiology. Like cocaine and morphine; nicotine causes addiction to tobacco. Cigarette smoking speeds up your heart beat and increases blood pressure. It is major cause of emphysema (chronic obstructive lung disease leading to damage of alveoli), chronic bronchitis, coronary heart disease (CHD) and lung cancer. Carbon monoxide along with nicotine increases the prevalence of heart attack in smokers.

The tar present in the smoke of cigarette or bidi damages the delicate epithelial lining of lungs. The brown and sticky deposit produced by the tar is a cause of lung cancer in smokers. The nicotine content per cigarette has been estimated to 20-30 mg. The carbon monoxide remains in the blood of a smoker for 5-6 hours after he finishes a cigarette and keeps interacting with body metabolites and drugs. The tobacco that is chewed, kept in the mouth or snuffed has equally bad effects. The consumption of tobacco is like ‘slow motion suicide’ due to its bad effects and inimical interaction with large number of drugs taken for various health ailments:


Tobacco has been found to reduce the effectiveness of pain killers (analgesics), anti-asthma drugs, anti-coagulants and drugs used to treat heart ailments. The risk of cardiovascular diseases increases in women taking oral contraceptives.

Risks for a Pregnant Smoker !

The period of gestation, number of pregnancy and general health of a pregnant woman with smoking habit are the important factors which could influence the effect of smoking on the unborn baby. When a pregnant woman smokes, her unborn baby does the same. The carbon monoxide and nicotine are passed onto unborn baby through blood stream. The maternal blood laced with nicotine and enriched with carbon monoxide lessens the oxygen supply and accelerate the heart beat of unborn baby. The child is likely to be premature or under weight. The growth of the toddler would be affected and the child may be more susceptible to infectious diseases. The chances of spontaneous abortions and still-births are three times more in pregnant smoker as compared to non smoker pregnant. The risks are more pronounced in pregnant smokers with anemia and poor nutrition.

A non-smoker pregnant woman, whose husband smokes, would be having identical risks for her unborn baby. In fact a non-smoking wife of a smoker husband thus becomes a non-smoking smoker or passive smoker. Pregnant smokers and the husbands of non-smoker pregnant women should quit smoking for the better outcome of pregnancy and the health of their baby. Excessive smoking during first trimester of pregnancy may lead to abortion. Primigravida women ( women with first pregnancy) would be at more risk as compared to multigravida due to pregnancy associated physiological and metabolic changes as well as psychological and emotional factors.